How to Use DMSO for Weight Loss

DMSO is a solvent but it also has many benefits for health. It will dilate your blood vessels and reduce inflammation and is a natural diuretic to help reduce fluid retention.

It has been used to help with weight loss but also to treat interstitial cystitis and many other conditions.

Here, I’ll explain how DMSO works, how to use it, and share some tips to help you on your weight loss dream.

What is DMSO?

Dimethyl sulfoxide, commonly referred to as DMSO, is a multifunctional organic substance that stands out due to its impressive solvent abilities and role as a cryoprotectant.

It’s able to penetrate biological membranes in a way that almost nothing else does. Because of this it is being studied for a variety of medical and therapeutic uses.

It has two effects depending on the dosage you use. At a low dosage it is an antioxidant and helps protect cells.

At a higher dosage it is oxidizing and toxic to cells. If your are considering it for weight loss, be sure to use a low dose and do a small trial before using it for that purpose.

DMSO Metabolism & Weight Loss in Fat Cells

Lab tests show DMSO at 10% concentration and higher melts fat in fat cells. This is important because it suggests DMSO can alter how our body stores fat.

The way DMSO works changes at different concentrations. At lower concentrations, it increases the energy production in fat cells.

This can boost metabolism and may help the body burn more fat for energy. This is a great benefit for people who have a slow metabolism.

Another benefit that helps with weight loss is DMSO’s ability to reduce water retention.

By altering the way water moves through cells, it can help reduce bloating and lower overall body weight, which is often water.

Combine this with its effects on fat cells and DMSO becomes a great supplement for anyone on a diet.

The key to DMSO weight loss is the concentration. Lower concentrations can increase metabolism and help the body burn more fat for energy.

Higher concentrations can harm metabolism and damage tissues. So, use it wisely and at the right concentrations for the benefits you desire.

Proper dosing of DMSO for effective weight loss.

How Does DMSO Help with Weight Loss?

DMSO has been shown to affect lipid metabolism, making it a potential fat burner.

Research has shown that DMSO interacts with lipids in fat cells, decreasing lipid content by up to 90% at concentrations of 10% or more. This implies that DMSO may alter how your body stores fat.

At low doses, it has been shown to increase mitochondrial activity in fat cells, which can increase metabolism and energy expenditure. This is a good thing if you’re trying to lose weight and burn fat for fuel.

DMSO’s diuretic properties can also help with water retention, which can make a big difference in how you look and feel. When you’re not bloated, you’ll notice in the mirror and in your clothes.

Choose the Best DMSO for Weight Loss

The type of DMSO you use makes a big difference when it comes to applying it for weight loss.

You can get DMSO in gel, cream, or liquid form. Each has its own advantages and disadvantages.

Gels and Creams: These are the most common forms of DMSO. They are easy to apply and allow you to target specific areas of your skin. They can be messy, but they are generally easier on the skin than liquids and less likely to cause irritation.

Liquids: These can be very effective, but they often have a strong odor and can be irritating to the skin. If you do opt for a liquid DMSO, be sure to prepare your skin and use it sparingly to help it absorb.

You’ll also want to be careful not to get it on your clothes or in crevices of your skin.

How to Use DMSO Safely ?

To use DMSO, make sure your hands and skin are thoroughly clean. It increases absorption, so any impurities on your skin can be absorbed into your body.

If you’re new to DMSO, start with a 25% blend and gradually work your way up. Always use pharmaceutical-grade and do a patch test on a small area of skin before applying it to your desired spot.

When applying it, use clean cotton balls or brushes to treat the area.

After applying, avoid exposing your skin to toxic substances for at least three hours, as your skin will be more permeable during this time.

This allows your skin to absorb beneficial compounds more effectively.

My Note :

Be sure to talk to your doctor before using DMSO or any weight loss product, even if you find it at a health food store or natural product.

You could be allergic to one of the ingredients in it, and your doctor can help you determine that.

They can also tell you how much DMSO you should use based on your individual body needs. So please don’t use it without first consulting your doctor.

DMSO for weight loss: does it work?

DMSO Benefits

We’ve all been there: carrying a few extra pounds we’d love to shed. it can definitely help with that (we’ll get to that in a minute).

But DMSO is so much more than a weight loss supplement. Here’s why:

Intestinal Circulation

DMSO increases blood flow to your intestines. This allows your body to absorb nutrients more efficiently, creating healthier tissue.

If you have circulation issues or heart problems, this benefit alone is worth considering DMSO.

Intestinal Barrier Function

It helps preserve the proteins that keep your intestinal barrier intact. A healthy intestinal barrier is essential for a functioning digestive system and prevents diseases associated with leaky gut.

Potentizing Anti-Inflammatories

DMSO can make non-steroidal anti-inflammatory drugs (NSAIDs) work more effectively while reducing their damage to healthy cells. This makes it a great companion for managing inflammation and conditions like arthritis.

Potentizing Antioxidants

Even at low doses, DMSO has been shown to increase glutathione production in your cells. Glutathione is your body’s main antioxidant, so this is a big deal!

Cellular Effects

It affects how your cells respond to proteins, which has a number of positive effects. By decreasing oxidative stress and increasing superoxide dismutase (SOD) activity, it’s a great all-around health supplement.

In other words, DMSO is so much more than a weight loss supplement; it’s a health and wellness powerhouse.

DMSO for Weight Loss: Does It Work?

Research is mixed but promising. At high concentrations (1% or higher), DMSO is toxic to fat cells and can create oxidative stress so dosage is important.

Low concentrations of DMSO don’t seem to affect fat cells, but higher concentrations significantly decrease fat content.

The World Health Organization suggests we need to understand how substances like DMSO impact our metabolism in order to create effective weight loss strategies.

The catch is DMSO may affect fat metabolism and increase free fatty acids, but it depends on the dosage.

On a positive note, low concentrations might have antioxidant effects. Higher concentrations decrease glutathione levels, which makes weight loss a tricky goal.

Use it with caution and at very low concentrations if you’re trying to lose weight.

The Dangers of DMSO

While DMSO is not inherently safe, it can be dangerous to use it without following proper safety precautions. Here’s what you need to know:

Don’t Overdo It

Using high concentrations of DMSO (1% or higher) can be toxic to your cells and decrease their ability to survive. Taking high doses of DMSO can increase negative metabolites in your body and create stress in your fat cells.

Allergic Reactions

Some people are highly sensitive to DMSO and may experience strong allergic reactions, headaches or a burning sensation on their skin.

If you’re pregnant or breastfeeding, it’s best to avoid DMSO altogether since its effects on babies are not fully understood.

Side Effects

Stomach upset, skin irritation and a pungent garlic smell are common side effects of DMSO.

To avoid complications and get the best results, always wash your hands and the area you plan to treat before using it.

Always consult your doctor before starting any treatment.

Clinical Trials and Research

Clinical trials and research have proven DMSO’s weight loss benefits. Studies show that applying DMSO at 10% and 100% can reduce fat in adipocytes by 14% and 47% respectively, it can break down fat.

Combining it with other weight loss medications may intensify the effectiveness and precision of the treatment.

Studies show that when adipocytes are treated with lower concentrations of DMSO, glutathione levels increase, it may also have antioxidant properties.

Research also shows DMSO can modify protein expression which is part of its weight loss benefits.

Higher doses of DMSO seems to slow down 3T3-L1 metabolic processes, so dosing should be done with care.

This support DMSO’s role in weight management but more research is needed to know its overall metabolic effects.

Final Verdict

DMSO is a very interesting substance that can assist with weight loss and it has other benefits for our bodies as well. It can modify how our body metabolizes fat, it increases the way our cells produce energy, and it’s a very potent diuretic.

So if you’re looking to lose some weight, DMSO can be very helpful. Just use it with caution because it can cause some negative side effects if you’re not careful.

Always consult with a healthcare professional before using it.

Dr. Clifton Morris
Dr. Clifton Morris

Meet Dr. Clifton Morris, MD. He's a highly accomplished medical professional with an impressive career. He graduated from University Of North Carolina in 1994

He's also a Senior Cardiometabolic Faculty at Baim Institute for Clinical Research.

He did his training in Internal Medicine at Brigham and Women’s Hospital and specialized in Gastroenterology and Cardiac Ultrasound at Tricities Hospital..