What Are the Side Effects of the Wormwood Herb? 7 Risks Explained

Wormwood herb could appear like a natural remedy, but it comes with concealed dangers you should know about. While it’s been utilized for centuries, modern research highlights serious risks, from neurological issues to harm for expecting mothers. Should you be contemplating it, comprehending these side effects could save you from unexpected trouble. Let’s analyze the seven key risks so you can make an informed choice—your health depends on it.

Neurological Effects Due to Thujone Content

Since wormwood contains thujone, a compound that affects your brain, you could experience serious side effects whenever taken in excessive amounts.

Thujone is neurotoxic, meaning it can harm your central nervous system. High doses may trigger seizures, muscle spasms, or nausea, especially in case you have epilepsy.

Even small amounts over time can cause neurological effects like restlessness or confusion. The risks increase should you consume unregulated products with high thujone levels.

Your brain’s sensitivity to this compound means even moderate use could lead to problems. Always check labels and avoid wormwood if you’re prone to seizures or other nervous system issues.

Liver and Kidney Toxicity From Long-Term Use

Should you use wormwood long-term, you could risk liver damage because thujone can harm your liver over time.

Your kidneys could also suffer, as thujone has been linked to kidney problems, particularly in case you already have issues.

Watch for signs like nausea or fatigue, since they may signal liver or kidney stress.

Potential Liver Damage

Long-term use of wormwood, especially products with thujone, can seriously harm your liver and kidneys.

Thujone, a key compound in wormwood, might cause liver toxicity and hepatotoxicity, straining your liver over time. Symptoms like jaundice, abdominal pain, or elevated liver enzymes signal trouble.

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Prolonged use increases health risks, as thujone builds up in your body, potentially leading to renal damage or even acute renal failure.

The FDA recommends avoiding thujone-containing products due to these dangers. Should you have been using wormwood chronically, watch for warning signs and consider safer alternatives to protect your liver and overall well-being.

Kidney Function Impairment

Wormwood doesn’t just affect your liver—it can also take a toll on your kidneys, especially with long-term use.

The thujone in wormwood products might cause kidney toxicity, leading to nephrotoxic effects that impair renal function. Should you have pre-existing kidney conditions, this risk increases, potentially escalating to acute renal failure or even kidney failure.

While short-term use of thujone-free wormwood is generally safer, prolonged exposure still raises concerns.

Always check labels for thujone content and consult a healthcare provider should you be unsure. Your kidneys work hard—don’t make their job harder by overlooking these risks.

Risks for Pregnant and Nursing Women

While wormwood has been used for centuries in traditional remedies, it’s not safe for everyone—especially in the event you’re pregnant or nursing. The thujone in wormwood could cause adverse effects, like disrupting fetal development or even increasing miscarriage risk.

Since safety during lactation isn’t well-studied, it’s best to avoid it while nursing too. Thujone might potentially harm your baby through breast milk.

Always consult your healthcare provider before using wormwood or any herb, as the risks outweigh unproven benefits. Though naturally derived, wormwood isn’t worth risking your pregnancy or your child’s health. Stay cautious and prioritize proven-safe alternatives.

Allergic Reactions and Skin Sensitivities

Should you have ever had a bad reaction to plants like ragweed or daisies, you could want to be careful with wormwood.

As part of the Asteraceae family, it can trigger allergic reactions, especially when you’re prone to herb sensitivity.

Contact dermatitis is common—itching, redness, or swelling could show up after topical application. Even handling the plant could cause skin sensitivities.

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In some cases, nausea follows exposure, signaling your body’s rejection. Should you notice these signs, stop use immediately.

Always patch-test new products and consult a doctor in case you’re unsure about past reactions to similar plants.

Stay safe and listen to your body.

Digestive Disturbances and Gastrointestinal Issues

Should you have ever felt queasy after trying a new herb, wormwood could cause similar discomfort. Its bitter compounds could irritate your digestive tract, leading to nausea, vomiting, or diarrhea.

Stomach cramps can also flare up, especially in case you take concentrated forms like extracts. High doses may worsen digestive disturbances, leaving you bloated or uneasy.

In case you’ve got pre-existing digestive disorders, wormwood’s adverse effects could hit harder. While it could help digestion for some, improper use often backfires.

Always start small and watch for signs your gut isn’t happy—your body will tell you when it’s not the right fit.

Potential Drug Interactions and Medication Conflicts

You should be cautious mixing wormwood with anticonvulsants, as it may make them less effective and raise your seizure risk.

Should you be on blood thinners like warfarin, wormwood can increase bleeding chances, so check with your doctor initially.

Since thujone in wormwood affects your nervous system, combining it with other thujone-heavy products could cause extra side effects.

Anticonvulsant Medication Risks

Because wormwood contains thujone, a compound that can affect the nervous system, mixing it with anticonvulsant medications might make those drugs less effective. Should you take anticonvulsants for seizures or epilepsy, wormwood could increase your risk of breakthrough seizures. Thujone’s stimulating effect can counteract your medication, so it’s vital to talk to healthcare providers before trying herbal remedies like wormwood. Monitoring your response is key to avoiding interaction risks.

Risk FactorWhy It Matters
Thujone in wormwoodMay reduce anticonvulsant effectiveness
Breakthrough seizuresHigher risk for individuals with epilepsy
Need for medical adviceGuarantees safe use with your current meds

Always prioritize safety—ask initially.

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Blood-Thinning Herb Interactions

While wormwood has been used for its potential health benefits, it’s essential to know how it could interact with blood-thinning medications like warfarin.

The thujone in wormwood could increase your risk of bleeding or hematoma formation combined with anticoagulants, making effects unpredictable. Should you be on blood-thinning medications, wormwood might amplify their action, raising concerns.

Always talk to your healthcare provider before mixing herbal supplements like wormwood with anticoagulants or antiplatelet drugs. Even small interactions could lead to serious complications, so monitoring is key.

Don’t assume herbal means harmless—unpredictable interactions can happen, and your safety comes foremost.

Kidney Function Impact Concerns

Taking wormwood as a supplement could raise concerns for those with existing kidney issues, since its active compound, thujone, can be tough on the kidneys.

Thujone’s nephrotoxic properties might worsen kidney function, especially in the case of chronic kidney disease. High doses or long-term use could lead to adverse effects, including renal failure.

Should you be on blood-thinning medications like warfarin, wormwood might increase the strain on your kidneys. Always check with healthcare providers before mixing supplements and meds.

Stick to recommended dosage to lower risks. In the event that your kidneys are already struggling, play it safe—skip wormwood or get professional advice initially.

Contraindications for Children and Severe Health Conditions

Wormwood isn’t safe for kids—their bodies aren’t equipped to handle thujone, a compound in the herb that can cause serious harm in small doses.

The toxicity risks are higher for children and those with severe health conditions, like chronic kidney or liver issues, where wormwood could trigger kidney failure.

Should you be pregnant, avoid it entirely—it could harm you or your baby.

Should you have allergies to ragweed or marigolds, steer clear, as reactions can be severe.

Also, should you be on anticoagulant or anti-seizure medications, wormwood may worsen side effects.

Always check with your doctor before trying it.

Matthew Solan
Matthew Solan

Matthew Solan, MS, RDN, CDN, is a coach who has guided over 500 people with flexible dieting. Editor of The Allfit Well, he leads by example in fitness.
With degrees in biology and education and certifications in Fitness Nutrition and Training, he is a registered dietitian in Florida. Matthew is an expert in fitness, nutrition, and diets, staying updated through peer-reviewed scientific studies and expert interviews.