Flu vs Strep: What’s the Difference?

Strep throat is a bacterial infection caused by Group A Streptococcus, characterized by severe sore throat, fever, and swollen glands, and is treated with antibiotics.

And the flu is a viral infection that affects the entire respiratory system, presenting symptoms such as cough, body aches, and high fever, and is managed with antiviral medications if treated early.

But Strep throat vs flu: how can you tell the difference?

Let’s take a closer look at how these two disease, flu vs strep differ. 

What is Strep Throat?

Strep throat is a painful infection caused by Group A Streptococcus bacteria, also known as Streptococcus pyogenes.

This bacteria infects your throat and tonsils, causing severe throat pain and difficulty swallowing. Unlike the flu, strep throat does not come with a runny nose or cough.

Strep throat symptoms are intense, with throat pain, high fever, and swollen glands in your neck. Adults often have inflamed tonsils, while kids have enlarged lymph nodes. It can be so painful that you have trouble eating or drinking.

When doctors diagnose strep throat, they look for redness and swelling in your throat, often with white patches. To confirm the presence of those troublesome bacteria, a quick swab test is performed on the back of your throat.

What is the Flu ?

Now let’s talk about the flu. Influenza, or the flu, is a highly contagious virus that affects your entire respiratory system. It brings along a whole host of symptoms, making it more widespread than strep throat. Common flu symptoms include:

  • High fever
  • Coughing fits
  • Nasal discharge
  • Body aches
  • Extreme fatigue

Sometimes, ear infections can sneak in as part of the flu package, too.

Flu symptoms usually hit you like a freight train, and they can be much worse than a common cold.

For those at higher risk, like seniors or individuals with weakened immune systems, the flu can lead to serious complications such as pneumonia. It spreads rapidly through contact with infected individuals or contaminated surfaces, especially in crowded places.

To combat the flu, getting vaccinated is a smart move. The peak flu season runs from December to February, but getting your shot early will keep you protected throughout that time.

Strep Throat vs Flu

Strep throat symptoms typically show up suddenly as a severe sore throat, without the accompanying respiratory symptoms like coughing or a runny nose.

On the other hand, flu symptoms emerge quickly and can include body aches, coughs, and congestion that affect your overall well-being.

Both are caused by different pathogens, which means they require different treatments. Strep throat is a bacterial infection treatable with antibiotics, while the flu is caused by viruses that can be managed with antiviral medications if caught early.

Below I’ve make key differences table about flu vs Strep.

FeatureFlu (Influenza)Strep Throat
CauseCaused by influenza viruses (Type A, B, or C)Caused by Group A Streptococcus bacteria
OnsetSudden onset of symptoms, often within hoursSudden onset of sore throat, typically over hours
Primary SymptomsFever, cough, fatigue, body aches, sore throat, headacheSevere sore throat, pain when swallowing, swollen tonsils with white patches
FeverCommon, moderate to high (100°F–104°F)Common, often high (above 101°F)
CoughCommon and persistentRare or mild
Runny NoseCommonRare
Body AchesCommon and widespreadRare
Swollen Lymph NodesMild swelling in some casesCommon, especially in the neck
ContagionHighly contagious via respiratory dropletsContagious via respiratory droplets or direct contact
DiagnosisBased on symptoms; confirmed with rapid flu test or PCRThroat culture or rapid strep test
TreatmentAntiviral medications (e.g., oseltamivir) if diagnosed early; rest and hydrationAntibiotics (e.g., penicillin or amoxicillin)
Duration1–2 weeks, with gradual recovery3–7 days with treatment
ComplicationsPneumonia, sinus infections, or worsening of chronic conditionsRare complications like rheumatic fever if untreated
PreventionAnnual flu vaccine, hand hygieneGood hygiene, avoid close contact with infected people

Diagnosis Methods including Rapid Strep Test

Strep throat can be diagnosed through a physical examination and a throat swab. The rapid strep test can detect strep bacteria in just minutes.

For more sensitive detection, PCR (polymerase chain reaction) tests can identify tiny amounts of bacterial DNA. Throat cultures are another method, but they can take up to two days for results.

To quickly diagnose the flu, rapid flu tests using nasal swabs can detect influenza viruses. These tests provide fast results, allowing for prompt care.

Read More: Heavy Legs Feeling : Causes and Natural Remedies

Treatment Options

Getting the right treatment for strep throat and the flu is essential because they require different approaches.

Antibiotics can effectively combat strep throat by targeting the bacteria, but it’s vital to complete the entire course to clear the infection and prevent complications.

If you catch the flu, early diagnosis can lead to antiviral medications that inhibit the virus from multiplying.

This can reduce symptoms and shorten recovery time. However, these medications won’t work against bacterial infections like strep.

Treatment varies between strep throat and the flu due to their different causes: one is bacterial, and the other is viral.

Note: Quick action and following your doctor’s advice will ensure a fast recovery from either condition.

When to See a Doctor

If you experience severe throat pain, difficulty swallowing, or a high fever from strep throat, don’t hesitate to see a doctor. Ignoring treatment can lead to serious outcomes like rheumatic fever, which can affect your heart health.

For flu symptoms such as respiratory issues, persistent chest pain, or high fever, it’s crucial to see a doctor right away. Influenza can be serious, especially for high-risk groups like seniors or those with chronic health conditions.

10 Ways to Prevent Flu Season

The CDC’s Weekly U.S. Influenza Surveillance Report for Week 52, ending December 28, 2024, shows that 6.8% of patient visits were for respiratory illnesses like fever, cough, or sore throat.

This is widely known as influenza-like illness (ILI). This number is above the national average of 3.0% for the fifth week in a row, showing how common the flu has been this season.

Of course, you can prevent it directly. Here are ten effective ways to keep both strep throat and the flu at bay:

  • Hand Washing

Wash your hands frequently and thoroughly to stop the spread of germs.

  • Limit Close Contact

Steer clear of people showing respiratory symptoms to minimize your risk of infection.

  • Tissue Use

Always cough or sneeze into a tissue, then toss it to prevent germ spread.

  • Sanitize High Touch Areas

Clean and disinfect surfaces that are frequently touched to kill germs.

  • Vaccination

Getting your annual flu shot significantly reduces your chances of catching the flu.

  • Hydration

Stay hydrated to keep your immune system strong.

  • Nutrient-Rich Food

Fuel your body with nutrient-rich foods to bolster your defenses against illness.

  • Avoid Sharing Personal Items

Don’t share utensils or personal items with infected individuals.

  • Stay Home When Sick

Isolate yourself at home if you’re feeling unwell to prevent spreading illness.

  • Monitor Flu Season

Keep an eye out during peak flu months to stay informed.

    Following these tips will help reduce your chances of getting sick with either condition and promote overall health.

    Bottom Line

    According to studies, every year, 3–5 million severe cases of influenza-associated acute respiratory infections require hospitalization around the world. In poor countries, 90% of these hospitalizations are for children under five.

    As you can see, flu and strep both are common illnesses that require accurate diagnosis, swift action, and informed steps to protect yourself and others. After all, timely care can prevent serious complications from these conditions.

    References:

    • Centers for Disease Control and Prevention. “Estimated Burden of Influenza: Questions and Answers.” CDC.gov, Centers for Disease Control and Prevention, 2024.
    • “Interaction Between Influenza Viruses and Streptococcus Pneumoniae.” PubMed, National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/35088451
    • Iuliano, A. Diane, et al. “Estimates of global seasonal influenza-associated respiratory mortality: A modelling study.” The Lancet, vol. 391, no. 10127, 2018, pp. 1285-1300. National Center for Biotechnology Information, doi:10.1016/S0140-6736(17)33293-2.

    John Harvey
    John Harvey

    John Harvey M.D., M.P.H. is the Director of VA Greater Los Angeles Healthcare System and a Professor at T.H Chan School of Public Health . As an Internal Medicine physician at Boston Healthcare System, I aim to improve healthcare quality and costs through policy-focused research. I earned my M.D. and M.P.H. from Harvard, and completed fellowships at University of California, San Francisco.